NON-INVASIVE EXPLORATION
Multi-modal imaging dedicated to the non-invasive exploration of small animals.
Possibility of longitudinal monitoring with maintenance of animal health status.
Expertise
The department is composed of engineers with expertise in molecular imaging and data analysis, a researcher specializing in MRI, and a technician specialized in animal experimentation.
Specificity
Maintenance of the SPF health status of rodents entrusted to the department (all procedures) is ensured by the use of containment cells adapted for MRI, PET and CT procedures.
Services
Scientific collaborations, research and development, and service delivery. The department is open to both academics and private companies. Participation in regulatory (UPAL) and internal training courses.
Magnetic Resonance Imaging (MRI)
IRM/SRM 7T (Bruker)
ENI - Oncopôle
- High-resolution anatomical imaging
- Functional imaging
- Spectroscopic analysis (SRM)
Nuclear imaging with PET / CT
- PET imaging [18F], [89Zr]
Static or dynamic acquisition
Quantification (% ID, % ID/g, SUV, etc.)
Atlas repositioning
Ex vivo biodistribution
- Anatomical imaging
Imaging of the skeleton and dentition
Detection of pulmonary metastases by CT imaging and thresholding
Imagerie Ultrasonore
Aixplorer (Ultrasonic imaging)
ENI - Oncopole
- Anatomical imaging:
Applications in oncology (detection and monitoring of tumor growth)
- ShearWaveTM Elastography
Real-time visualization and analysis of tissue hardness, which assist in the early detection of lesions in a homogeneous organ.
Vevo2100 (Visualsonics) - High-resolution ultrasound scanner designed for small animal imaging
ENI - Rangueil
- Anatomical imaging:
cardiovascular, cancer, developmental biology
- Cardiovascular functional imaging:
Longitudinal studies of cardiac remodeling, measurements of systolic and diastolic function, ejection fractions, strain
- Flux study:
Color doppler et Pulse-Wave Doppler
Bioluminescence and fluorescence imaging
IVIS Spectrum (Perkin Elmer)
Purpan
- Bioluminescence and fluorescence imaging
- Longitudinal monitoring of physiological and pathological phenomena (tumor growth), as well as the study of cell migration in a simple, rapid, non-traumatic manner in living animals.